| abstract |
The present application relates to derivatives of 1,2,3,4,4a, 5,6,7-octahydropyrazine [1,2-a] [1,4] benzodiazepine, 1,2,3,4,4a, 5 , 6,7-octahydropyrazine [1,2-a] [1,5] benzodiazepine, 2,3,4,4a, 5,6,7,11b-octahydro-1H-pyrido [3,4-d] [2 ] benzazepine, 1,2,3,4,4a, 5,6,7-octahydropyrazine [1,2-aJ [1] benzazepine, 1,2,3,4,4a, 5-hexahydro-7H-pyrazine [1 , 2-a] [4,1] benzoxazepine, and 2,3,4,4a, 5,6-hexahydro-1H-pyrazino [2,1-d] [1,5] benzoxazepine, and 5,6,7 , 7a, 8,9,10,11-octahydropyrazino [1,2-d] pyrido [3,2-b] [1,4] diaz epine of the formula (I) in which R1, R2, R3, R4 , R5, R6, X1, X2, X3, X4, Y1, Y2, and Y3 are as defined in the description. The present application also relates to compositions comprising said compounds, and to methods for treating pathological conditions using said compounds and compositions, and to methods for identifying said compounds. |