| abstract |
The present invention relates to piperidine and pyrerazine derivatives according to formulas (la), (Ib) and (II) as autotaxin inhibitors, and with the use of such compounds for the treatment and / or prophylaxis of physiological conditions and / or pathophysiological that are caused, mediated and / or propagated by increased levels of lysophosphoric acid and / or the activation of autotaxin, in particular of different cancers. |