abstract |
The present invention relates to a complex between an insulin and a polysaccharide comprising carboxylic functional groups, said polysaccharide is selected from the polysaccharides functionalized by at least one phenylalanine derivative, in particular Phe said phenylalanine derivative is selected from the group consisting of phenylalanine. and its alkali cation salts, phenylalanine, phenylalanine amide, ethylbenzyl amine or between the phenylalanine esters and insulin shower is either a human insulin or insulin analog. The invention also relates to a pharmaceutical composition comprising at least one complex according to the invention, particularly in the form of an injectable solution. |