http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2011009489-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9cf7ff1f08310f0557c06b9a0f910a9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-495 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2010-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc99776e5ea322d90a0c03605950801a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_33fd454aa8e1dd7cd8316a705ca540a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc99a821ee9b42ff300980b01c5b979 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a45c5b0e838739da37c1ea1034b9b409 |
| publicationDate | 2011-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2011009489-A |
| titleOfInvention | PIRROLO DERIVATIVES [2,3-B] PIRIDINE FOR THE INHIBITION OF RAF KINASES. |
| abstract | The {2,4-difluoro-3- [5- (2-methoxy-pyrimidin-5-yl) -1 H-pyrrolo [2,3-b] pyridine-3- propane-1-sulfonic acid compounds are described carbonyl] -phenyl} -amide, [3- (5- cyano-1 H -pyrrolo [2,3-b] pyridine-3-c arbonyl) -2,4-difficult-phenyl] - propane-1-sulfonic acid - amide, [3- (5- cyano-1 H -pyrrolo [2,3-b] pyridine-3-carbonyl) -2-fluoro-phenyl] -amide propane-1-sulfonic acid, N- [3- (5 -cyano-1H-pyrrolo [2,3-bJpyridine-3-carbonyl) -2,4-ciifluoro-phenyl] -2,5-difluoro-benzenesulfonamide, N- [3- (5-cyano-1H-pyrrolo [2 , 3-bjpyridine-3-carbonyl) -2,4-difluoro-phenyl] -3-fluoro-benzenesulfonamide, [3- (5- cyano-1H-pyrrolo [2,3-b] pyrrolidine-1-sulfonic acid) pyridine-3-carbonyl) -2,4-difluoro-phenyl] -amide, [3- (5-cyano-1H-pyrrolo [2,3-b] pyridine-3-carbonyl] N, N-dimethylamino-sulfonic acid ) -2,4-difluoro-fe nil] -amide, and salts thereof, formulations thereof, conjugates thereof, derivatives thereof, forms thereof and uses thereof. In certain aspects and embodiments, the described compounds or salts thereof, formulations thereof, conjugates thereof, derivatives thereof and forms thereof are active on at least one Raf protein kinase. Methods of using them to treat diseases and conditions, including diseases and conditions associated with the activity of Raf kinase proteins, including melanoma, glioma, colorectal cancer, thyroid cancer, lung cancer, ovarian cancer, cancer are also described. of prostate and biliary tract cancer. |
| priorityDate | 2009-03-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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