abstract |
Novel sirtuin modulation compounds and methods of use thereof are provided herein; Sirtuin modulation compounds can be used to increase the half-life of a cell and treat and / or prevent a wide variety of diseases and disorders that include, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer and / or suffocation as well as diseases or disorders that would benefit from increased mitochondrial activity; Compositions comprising a sirtuin modulation compound in combination with another therapeutic agent are also provided. |