abstract |
The present invention relates to a screening method for a non-endothelial synthase expression (eNOS) modulator, a method for diagnosing cardiovascular disease in a subject, the use of HEBP-1 for the identification of a medicament to prevent and / or treating a disease that involves eNOS dysfunction, particularly a cardiovascular disease, the use of HEBP-1 for the detection of a component of the transduction of the eNOS signal, and the use of HEBP1 for the regulation of the activity of the eNOS promoter. |