| abstract |
The present invention relates to new compounds of formula (I) and their pharmaceutical compositions. Additionally, the present invention relates to therapeutic methods for the treatment and / or prevention of Aβ-related pathologies such as Down syndrome, β-amyloid angiopathy such as, by way of taxation, cerebral amyloid angiopathy or hereditary cerebral hemorrhage, associated disorders with cognitive deficiency such as, non-taxatively, mild cognitive impairment, Alzheimer's disease, memory loss, symptoms of attention deficit associated with Alzheimer's disease, neurodegeneration associated with diseases such as Alzheimer's disease or dementia, including dementia of origin mixed vascular and degenerative, presenile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear paralysis or basal-basal degeneration. (See formula (I)). |