| abstract |
The invention relates to a class of pyrrolidine compounds of formula (I) (See formula (I)) and their pharmaceutically acceptable derivatives, their use in medicine, compositions containing them, and methods for their preparation; it also refers to intermediates used in the preparation of said compounds and derivatives; in particular, the compounds of formula (I) are useful for the treatment of disorders mediated by EP2, such as endometriosis, uterine fibroids (leiomyomata), menorrhagia, adenomyosis, primary and secondary dysmenorrhea (including symptoms of dyspareunia, dyskexia and chronic pelvic pain), chronic pelvic pain syndrome, polycystic kidney disease and polycystic ovary syndrome. |