http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2011004869-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f98e77d1aba3a9c2fb565cc42cc7c76f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-04 |
| filingDate | 2009-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d408d36c2f7d7823f911a95805ae4f3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7f5801a18204963d4bd851d6d03fe96 |
| publicationDate | 2011-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2011004869-A |
| titleOfInvention | ERBB-3 SELECTIVE COMBINATION THERAPY (HER3). |
| abstract | The invention relates to pharmaceutical compositions and methods of treatment with a combination therapy directed to HER3; The invention relates to pharmaceutical compositions comprising an oligomer that targets HER3 mRNA (and optionally one or more of HER2 and EGFR) in a cell, which leads to reducing the expression of HER3 and optionally HER2 and / or EGFR , and a small molecule protein tyrosine kinase inhibitor of one or more receptor tyrosine kinases, which leads to inhibiting signaling and / or internment of the receptor dimers in the cell; combination therapy is suitable for a range of medical disorders such as hyperproliferation disorders (eg, cancer); The invention provides methods of treating hyperproliferation disorders with a combination of an oligomer and a protein tyrosine kinase inhibitor. |
| priorityDate | 2008-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 348.