| abstract |
The present application describes novel benzimidazole derivatives of the general formula (I) or an N-oxide thereof, any of its isomers or any mixture of its isomers, or a pharmaceutically acceptable salt thereof; wherein R represents a pyridyl or pyrimidyl group; The pyridyl or pyrimidyl group is optionally substituted with one or more substituents independently selected from the group consisting of: halo, trifluoromethyl, trifluoromethoxy, cyano, nitro, alkyl, hydroxy, hydroxyalkyl and alkoxy, and their use as modulators of the GABAA receptor complex. In other aspects the application describes the use of these compounds, in a method for therapy and for pharmaceutical compositions comprising these compounds. |