http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2011004344-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b505465163764d31c1db0e966c2c9fbd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate | 2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9361adf9638f90d64bf4ea1fba7e4508 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d442aaed41113c953002c1face25e064 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f615ea844fa133b7acd6dc1b22e40b11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9472293207bfdc33783ff6277b858a70 |
| publicationDate | 2011-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2011004344-A |
| titleOfInvention | THERAPY AGAINST CANCER. |
| abstract | The invention provides therapy for treating cancers, such as Bcl-2 'cancers, and Bcl-XL' cancers, and other neoplasms, using romidepsin. The invention provides, inter alia, methods for treating lymphomas, for example, lymphomas characterized by one or more Bcl-2 expression, lack of Bcl-XL 'overexpression, lack of overexpression of P-glycoprotein, with romidepsin. In some modalities, lymphoma is a cutaneous T-cell lymphoma. In some modalities, lymphoma is a peripheral T-cell lymphoma. Romidepsin can be administered in doses ranging from 0.5 mg / m2 to approximately 28 mg / m2 (for example, 1 mg / m2 to 15 mg / m2, 4 mg / m2 to 15 mg / m2, 8 mg / m2 at 14 mg / m2, or from 4 mg / m2 to about 10 mg / m2). Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteosome inhibitor, or a kinase inhibitor. |
| priorityDate | 2008-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 625.