abstract |
Methods for the isolation and purification of antibodies from a sample matrix are described herein. One aspect of the present description is directed to the reduction / deactivation of samples generated in various stages of antibody purification. In a particular aspect, the methods herein use an acidification stage followed by one or more chromatographic stages. The chromatographic steps may include one or more of the following chromatographic procedures: ion exchange chromatography, affinity chromatography, and hydrophobic interaction chromatography. |