| abstract |
The present invention presents a compound having the formula AXB, where A is a peptide vent capable of increasing the transport of the compound through the blood-brain barrier or to particular cell types, X is a linker, and B is an agonist GLP-1 (v. Gr., Exendina-4 or an analog of exendina-4). The compounds of the invention can be used to treat any disease where increased GLPL-1 activity is desired, for example, metabolic diseases, such as obesity and diabetes. |