| abstract |
A pharmaceutical composition for the modified release is described, comprising (1) (R) -2- (2- aminothiazol-4-yl) -4 '- [2 - [(2-hydroxy-2-phenylethyl) acid anilide. amino] ethyl] acetic or, or a pharmaceutically acceptable salt thereof, (2) at least one additive that ensures the penetration of water into the composition and that has a solubility such that the volume of water required to dissolve 1 g of the additive it is 10 ml or less, and (3) a hydrogel forming polymer having an average molecular weight of approximately 100,000 or more, or a viscosity of 12 mPa • s or more in an aqueous solution of 5% at 25 ° C. |