http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2011003429-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D453-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-416 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D453-02 |
| filingDate | 2009-10-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7eaa81e19711e1e1ee4ab27501c4ea0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6382decde11d5ca2c336336e589aed08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31b7f9c6339142ba160abfe36a625820 |
| publicationDate | 2011-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2011003429-A |
| titleOfInvention | METHOD FREE OF DIAZONIO TO MANUFACTURE AN INTERMEDIATE COMPOUND OF INDAZOL IN THE SYNTHESIS OF THE AMIDAS OF ACID 5- (TRIFLUOROMETOXI) -1H-3-INDAZOLCARBOXILICO BICICLICO. |
| abstract | The present invention provides novel methods for the preparation of 5- (trifluoromethoxy) -1H-3-indazolcarboxylic acid (3), which is a precursor for the preparation of the bicyclic 5-trifluoromethoxy-1H-indazol-S-carboxylic acid amides of the Formula (1). The compounds of the formula (1) are active as agonists and partial agonists of the a-7 nicotinic receptor and are being studied for use in the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain, such as for the treatment of Alzheimer's disease and schizophrenia, as well as other psychiatric and neurological disorders. The present methods are useful for the preparation of compound (3) at upward scaling levels. |
| priorityDate | 2008-10-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.