| abstract |
The present invention relates to antibacterial compounds of formula I (See formula (I)) wherein "-----" is a bond or is absent, V is CH, CR6 or N; R0 is H or, if "-----" is a bond, it can also be alkoxy; Notably, R1 is H or halogen; when "-----" is a bond, U is CH or N, or, if "-----" is absent, U is CH2, NH or NR9 R2 is H, alkylcarbonyl or -CH2-R3 R3 is H , alkyl or hydroxyalkyl; R4 is H or, if n is not 0 and R5 is H, it can also be OH; R5 is H, alkyl, hydroxyalkyl, aminoalkyl, alkoxyalkyl, carboxyl alkoxycarbonyl; R6 is hydroxyalkyl, carboxyl, alkoxycarbonyl or - (CH2) q-NR7R8, q being 1, 2 or 3 and R7 and R8 being, independently H or alkyl or R7 and R8 together with the N atom which porta, a ring; R9 is alkyl or hydroxyalkyl; A is - (CH2) p-, -CH2CH2CH (OH) - or -COCH2CH (OH) -; G is substituted phenyl or G1 (See formula (G1)) or G2 (See formula (G2)) where q is O or S and X is CH or N; and Y1, Y2 and Y3 can each be CH or N; and n is 0 when A is -CH2CH2CH (OH) - or -COCH2-CH (OH) -, and n is 0, 1 or 2 when A is - (CH2) -p, p being 1, 2, 3 or 4, always that the sum of n and p is then 2, 3 or 4; and with salts of such compounds. |