| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69ece09bafee7e0c49d1f7951a3faa2c |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-44 |
| filingDate |
2009-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b8dc73259adaddf4bad88dc80555847e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ebd928af516df5a474d9aa542c7e2fa8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c806c11ba6fd1db39a429cb671cfedd5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d6423d6bafcd8ff175832c28238eca4 |
| publicationDate |
2011-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2010014565-A |
| titleOfInvention |
ISOINDOLONE AND METHODS OF USE. |
| abstract |
The invention is related to isoindolones of formula I with anti-cancer and / or anti-inflammatory activity and more specifically with MEK kinase inhibitory activity. The invention provides compositions and methods useful for inhibiting abnormal cell growth, treatment of a hyperproliferative disorder or treatment of an inflammatory disease in a mammal. The invention is also concerned with methods of using the compounds for diagnosis or in vitro, in situ and in vivo treatment of mammalian cells or associated pathological conditions. |
| priorityDate |
2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |