| abstract |
The invention relates to the 1,5-diazacarbazole compounds of the Formula (I), (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig) and (Ih ), which are useful as kinase inhibitors, more specifically, useful as cell cycle regulator kinase 1 (chk1) inhibitors, therefore useful as therapeutic for cancer. The invention also relates to compositions, more specifically to pharmaceutical compositions comprising these compounds and to methods for using them to treat various forms of cancer and hyperproliferative disorders, as well as to methods for using the compounds for in vitro diagnosis or treatment, in situ and in vivo of mammalian cells, or associated pathological conditions. |