| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-71 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6812
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-84 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-84 |
| filingDate |
2009-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97aef6d52e48394b79121fa1d7250dfd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b286e87c064b27c6aa236d6ec48ccd7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db8b479db971d99d832a456b8249ba1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba90f5352900369ed8ff73badb45a5cc |
| publicationDate |
2010-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2010011959-A |
| titleOfInvention |
METHODS FOR MONITORING THE MODULATION OF KINASE ACTIVITY OF THE RECEIVER OF THE FIBROBLAST GROWTH FACTOR AND USE OF SUCH METHODS. |
| abstract |
The present invention relates generally to in vitro diagnostic methods, in particular the use of a compound selected from the group consisting of fibroblast growth factor 23 (FGF23), inorganic phosphorus (P), the inorganic phosphorus product and Total calcium (P x tCa), osteopontin (OPN) and parathyroid hormone (PTH) as a biomarker. Such biomarkers can be used to monitor the modulation of the kinase activity of the fibroblast growth factor receptor (FGFR), in particular, its inhibition and / or the occurrence of side effects of FGFR inhibition. The invention also provides methods and kits related to these uses. |
| priorityDate |
2008-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |