| abstract |
In its many embodiments, the present invention provides certain 2-imino-3-methyl pyrrolo pyrimidone compounds, which include compounds of formula (II): (see formula II) and includes pharmaceutically acceptable tautomers, stereoisomers or salts or solvates of said compounds, stereoisomers or said tautomers, wherein R2, R3, R4, R5, R6, R7, R8 and R9 each is independently selected and is as defined herein; Also described are pharmaceutical compositions comprising one or more of said compounds, and methods for their preparation and use in the treatment of pathologies associated with beta amyloid protein (Aβ), which includes Alzheimer's disease. |