http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2010011329-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ee602c630e57f59c6cfc1c1634e36064 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-28 |
| filingDate | 2009-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f063afbeca9fa2655feb325ffecdb40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf906e4080bd03e27954efce1511a919 |
| publicationDate | 2011-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2010011329-A |
| titleOfInvention | ISOFORM SPECIFIC INSULIN ANALOGS. |
| abstract | A method of treating a mammal by administering a physiologically effective amount of an insulin analogue or a physiologically acceptable salt thereof, where the insulin analog exhibits more than twice as much binding affinity to the receptor isoform A (IR-A). of insulin than to insulin receptor B (IR-B) isoform. The insulin analog can be a single chain insulin analog or a physiologically acceptable salt thereof, which contains an insulin A chain sequence or an analog thereof and an insulin B chain sequence or an analog thereof. connected by a 4-13 amino acid polypeptide. A single chain insulin analog may exhibit greater in vitro insulin receptor binding to IR-A but less IR-B binding than normal insulin while exhibiting less than or equal IGFR binding than normal insulin. |
| priorityDate | 2008-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.