| abstract |
The present invention provides a highly safe pharmaceutical preparation that is effective for diseases caused by MMP-2 and / or MMP-9; The pharmaceutical preparation contains, as active ingredient, at least one member selected from the group consisting of tlazole derivatives represented by Formula (1): (see formula (1)) in which R1 represents a phenyl group which may have between 1 and 3 lower alkoxy groups as substituents on the phenyl ring, and R2 represents a pyridyl group which may have between 1 and 3 carboxyl groups as substituents on the pyridine ring, and their salts; said tlazol derivatives possess inhibitory activity of MMP-2 and / or MMP-9. |