| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8fb1456312aa7998c552f43f015e6bc |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-02 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-815 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-62 |
| filingDate |
2008-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49b1113df4edf5aa5e60876c0394bd8f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_048d60467ba189265149c034040b1b26
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b209341f6b2262fc3c42d22594fc5a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a00c7a9d0fc23797e18d9c737c0edb8a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feb3b75b5cd280466238c4934fcc13d8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d9030e40a95bc435863886ee70f9f5b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78aaaf21167bbb5ee9c9ba8486e75d60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6445d21c6c8044eea8bc2c32083d2048
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dad987a80f1f80655d2359e1bbf60696
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c8b8043f768b837ba3be9eca4c8c980
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5ecf4a61b0edb223e05112a7511925f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b19172d232a103a9e9b98220e1652c2 |
| publicationDate |
2010-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2010009033-A |
| titleOfInvention |
A METHOD FOR OBTAINING PURIFIED HETEROLOGICAL INSULINS EXPRESSED IN YEAST. |
| abstract |
The invention relates to methods of separation and / or purification of impurities that provide a purified heterologous protein product devoid of related impurities or with substantially minimal amounts of said glycosylated impurities. More specifically, the invention relates to the identification of glycosylated forms of insulin analogs such as post-expression characterized glargine impurities in yeast-based systems such as Pichia pastoris. The invention also relates to methods used to donate genes encoding insulin glargine protein; insert the related gene into a suitable yeast host; Produce recombinant strain culture, stimulate heterologous polypeptide expression, its secretion and post-fermentation purification and related enzyme conversions. |
| priorityDate |
2008-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |