http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2010008861-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef8d8a82fd7380682fc0828e58b5f89e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2866 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2086 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-138 |
| filingDate | 2009-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_445951a26424e3d6fb3bb15ee068061d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ddc8036378fad7cb902f138bb5bf96af |
| publicationDate | 2011-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2010008861-A |
| titleOfInvention | ORAL TABLET OF CONTROLLED LIBERATION WITH REDUCED MASS RELEASE EFFECT. |
| abstract | The present invention relates to an oral controlled-release tablet that provides a lower risk of massive alcohol-induced dose release; The tablet is formed by a core formed by a first compressed layer containing a swelling agent, a second compressed layer containing at least one therapeutically active ingredient and a pharmaceutically acceptable excipient, wherein at least one excipient is an excipient that controls the release rate and wherein the weight percent of excipients that are soluble in alcohol is not more than 35% relative to the weight of the layer; As an optional feature a third compressed layer containing a swelling agent and a coating surrounding the core, the coating is constituted by a polymer insoluble in an aqueous medium having an alcohol content of 0% v / va 40% v / v Therefore, upon contact with the gastrointestinal aqueous fluids, the upper compressed layer swells or expands and causes the top surface to be removed from the upper compressed layer and then this upper layer disintegrates allowing the release of the active ingredient to Starting from the defined surface area of the upper surface of the lower compressed layer with the coating covering its lower and lateral surfaces. |
| priorityDate | 2008-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 71.