| abstract |
The present invention relates to an intravaginal administration system for the controlled release of drospirenone and an estrogen and, optionally, also comprises one or more therapeutically active or health promoting substances able to provide and / or improve protection against bacterial and fungal infections, and / or improve protection against sexually transmitted diseases. The administration system comprises one or more compartments, each of which comprises a core and a membrane that covers the said core. The core and said membrane are composed essentially of the same polymer composition or a different polymer composition, where at least one compartment comprises drospirenone and at least one compartment, which may be the same or different from that comprising drospirenone, it comprises an estrogen or a mixture of drospirenone and an estrogen, and where the membrane or the membrane surface or at least one of the nuclei comprises said therapeutically active or promoter substance Of the health. |