| abstract |
The present invention provides a solid pharmaceutical preparation having superior disintegration properties and excellent solubility, resulting in adequate absorption of the active ingredients through the gastrointestinal tract; The solid pharmaceutical preparation of the present invention comprises: (a) 7-Chloro-5-hydroxy-1- [2-methyl-4- (2-methylbenzoylamino) benzoyl] -2,3,4,5-tetrahydro-1H- benzazepine and / or a salt thereof, (b) hydroxypropyl cellulose containing a hydroxypropoxy group in an amount of 50% by weight or greater; and (c) at least one member selected from the group consisting of carmellose, sodium carboxymethyl starch, crospovidone, and low-substituted hydroxypropyl cellulose with an average particle diameter of 30 mum to 70 mum, and a cumulative particle diameter of 90 % from 100 mum to 200 mum. |