http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2009013260-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3f29ceb315cc72cf6a89e0393ca3acd |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02 |
filingDate | 2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7904452a46837bea3ddcc1aa9c6660f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb7dff37c586aee16f526c350cf33b09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d6c4bcaa5d1371d1f0321d5dbdf4ae |
publicationDate | 2010-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | MX-2009013260-A |
titleOfInvention | HYBRID OPERON FOR THE EXPRESSION OF THE ANTIGENS OF THE COLONIZATION FACTOR OF ESCHERICHIA COLI ENTEROTOXICA. |
abstract | The present invention relates to a recombinant operon comprising a set of genes where there are at least two structural genes encoding at least two major subunits of the colonization factor (CFs) antigens associated with enterotoxic Escheri chia coli bacteria (ETEC). The host cell, such as an Escherichia coli cell, genetically designed to comprise such a recombinant operon, wherein the operon is located on an episomic element, such as a plasmid, or integrated into the host cell chromosome is further described. A method of producing a host cell capable of expressing from the operon at least two major subunits of the colonization factor antigens (CFs) associated with the enterotoxic Escherichia coli bacteria (ETEC) is also described. In addition, a diarrhea vaccine composition comprising at least such a host cell together with pharmaceutically acceptable excipients, buffers, and / or diluents is described. Finally, the use of the operon in the production of such a vaccine is described. |
priorityDate | 2007-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Predicate | Subject |
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isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID453034310 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID516892 |
Total number of triples: 18.