http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2009013260-A

Outgoing Links

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a3f29ceb315cc72cf6a89e0393ca3acd
classificationCPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522
classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-02
filingDate 2008-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7904452a46837bea3ddcc1aa9c6660f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb7dff37c586aee16f526c350cf33b09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4d6c4bcaa5d1371d1f0321d5dbdf4ae
publicationDate 2010-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-2009013260-A
titleOfInvention HYBRID OPERON FOR THE EXPRESSION OF THE ANTIGENS OF THE COLONIZATION FACTOR OF ESCHERICHIA COLI ENTEROTOXICA.
abstract The present invention relates to a recombinant operon comprising a set of genes where there are at least two structural genes encoding at least two major subunits of the colonization factor (CFs) antigens associated with enterotoxic Escheri chia coli bacteria (ETEC). The host cell, such as an Escherichia coli cell, genetically designed to comprise such a recombinant operon, wherein the operon is located on an episomic element, such as a plasmid, or integrated into the host cell chromosome is further described. A method of producing a host cell capable of expressing from the operon at least two major subunits of the colonization factor antigens (CFs) associated with the enterotoxic Escherichia coli bacteria (ETEC) is also described. In addition, a diarrhea vaccine composition comprising at least such a host cell together with pharmaceutically acceptable excipients, buffers, and / or diluents is described. Finally, the use of the operon in the production of such a vaccine is described.
priorityDate 2007-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

Incoming Links

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Total number of triples: 18.