| abstract |
Benzoxazole and benzothiazole compounds, and their oxides, esters, pro-drugs, solvates, and pharmaceutically acceptable salts thereof are disclosed. Compositions of the compounds, either alone or in combination with at least one additional therapeutic agent, with a pharmaceutically acceptable carrier, and the uses of the compounds, either alone or in combination with at least one additional therapeutic agent, are also disclosed. . The modalities are useful for inhibiting cell proliferation, for inhibiting the growth and / or metastasis of tumors, for the treatment or prevention of cancer, for the treatment or prevention of degenerative bone diseases such as rheumatoid arthritis, and / or for inhibit molecules such as CSF-1R. |