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filingDate 2008-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a89af08104dea233f3342a4a0aa1ced
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publicationDate 2010-02-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber MX-2009012041-A
titleOfInvention DERIVATIVES OF 1,3-DIHYDROIMIDAZOL-2-TIONA AS DOPAMINE-BETA-HYDROXYLASE INHIBITORS.
abstract The compound of the formula I and a method for its preparation are described, wherein R1, R2 and R3 are the same or different and mean hydrogens, halogens, alkyl, nitro, amino, alkylcarbonylamino, alkylamino or dialkylamino groups; R4 means -alkyl-aryl or -alkyl-heteroaryl; X means CH2, oxygen atom or sulfur atom; n is 2 or 3; including the individual (R) and (S) enantiomers or mixtures of enantiomers thereof; including pharmaceutically acceptable salts and esters thereof. The compounds have potentially valuable pharmaceutical properties for the treatment of cardiovascular disorders such as hypertension and chronic heart failure.
priorityDate 2007-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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