Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b6c593ae01767e2b472996157d32f9cf |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0095 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0015 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6951 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-165 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
filingDate |
2008-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_08122ac324e249803dd88fc3a9f41e6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cdb2d53fa32333f921bf2b72e8e0ae5b |
publicationDate |
2010-01-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
MX-2009011642-A |
titleOfInvention |
COMPOUNDS AND METHODS TO POWER THE SOLUBILITY OF FLORFENICOL AND STRUCTURALLY RELATED ANTIBIOTICS USING CYCLODEXTRINES. |
abstract |
The relatively low solubility of florfenicol (FFC) in water (1.3 mg / ml) limits its use in medicated drinking water systems for the treatment of lung diseases of pigs and poultry; current formulations use a high volume organic solvent to reach the required FFC concentration of 13.5 mg / ml in an automated proportioning mixing tank system, with practical disadvantages for users in the field; This invention relates to the effects of complex formation with natural and modified cyclodextrins on the aqueous solubility of FFC and antibiotics of related structure; In addition, this invention relates to the effects of polyethylene glycol (PEG-300) as a cosolvent in an FFC-cyclodextrin system to achieve the required dose of FFC in the mixing tank system and avoid high volumes of the organic solvent. |
priorityDate |
2007-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |