| abstract |
The invention provides a composition comprising a nanofiber polymer in which the fibers of the nanofiber polymer are aligned and a molecule is covalently appended, either directly or by means of a linker, to the nanofiber polymer. This molecule is capable of annexing either covalently or non-covalently to a member selected from an extracellular matrix component, a growth factor and combinations thereof. The invention also provides methods of manufacturing the composition and methods for using the compositions to add new tissue to a subject, such as a human. |