| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c539db959cc0106cab1662303f94fce |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31855
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T428-31678 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 |
| filingDate |
2007-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ce61a977f0fcf2d30b684951dddc12a5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ce3d89ce684807a02e8e9a970b354e2 |
| publicationDate |
2008-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2008013491-A |
| titleOfInvention |
COMBINATION OF ALOVUDINE AND ZIDOVUDINA IN A MOLAR RATIO OF 1: 100 TO 1: 350. |
| abstract |
Co-administration of alovudine and zidovudine is described in considerable relationships in excess of the prior art totally or substantially suppressing mitochondrial toxicity of alovudine in mitochondrial DNA depletion experiments. The invention thus provides pharmaceutical compositions comprising alovudine and zidovudine in a molar ratio in the methods of the range 1: 100 to 1: 350 and methods for the treatment or prophylaxis of multiple resistance of HIV comprising simultaneous or consequent administration of alovudine and Zidovudine in the characteristic molar relationship. |
| priorityDate |
2006-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |