| abstract |
Heterocyclic substituted tricyclic compounds of fused rings of the formula (see formula I) or a salt or solvate acceptable for pharmaceutical use of said compound, isomer or racemic mixture are described, wherein ------ represents an optional double bond, and where An, En, Mn, Gn, Jn, R3, n7, R8, R9, R10, R11, R32, R33, X, Y. B and Het are defined in the present invention and the remaining substituents are as defined in descriptive memory, as well as Pharmaceutical compositions containing them and a method for treating diseases associated with thrombosis, atherosclerosis, restenosis, hypertension, angina pectoris, arrhythmia, heart failure, and cancer by administering said compounds; Combined therapy with other cardiovascular agents is also claimed. |