abstract |
The use of reducing agents of alpha-hydroxycarbonyl compounds that are capable of forming cyclic dimers is provided; corresponding reduction methods of reducible compounds, particularly of prodrugs activated by reduction, are also provided; Examples of the alpha-hydroxycarbonyl compounds that are used are dihydroxyacetone, glycollaldehyde, glyceraldhyde, erythrose, xylulose, erythrulose, or 3-hydroxy-2-butanone. |