http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2008000461-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2cf7f3f36d20185ce15a2d1f04d5fdc1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 |
| filingDate | 2006-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c3f5f4a7bc82ecb9088f1b3340df37d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5a2b9c6cef578aec9ac54af641b65d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4edc8e6d60e76f8d35fb0a0248124831 |
| publicationDate | 2008-03-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2008000461-A |
| titleOfInvention | PIRIDAZINE COMPOUNDS AS INHIBITORS OF THE GLUCOGENO SINTASA CINASA 3. |
| abstract | Pyridazine compounds of the formula I are described which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), methods for preparing the compounds, compositions containing the compounds, and treatment methods where the compounds are used (see formula ( I)): in formula l ==== indicates a single link or a double link; X is O, S or N-R5; R1, R2 are independently selected from the group consisting of H, NH2, NH-C1-C6-alkyl, OH, = O, C1-C6-alkoxy, halogen, methyl, C2-C4-alkyl, C3-C4 -cycloalkyl, C3-C4-alkenyl, C1-C4-fluorinated alkyl, C3-C4-fluorinated cycloalkyl, C3-C4-fluorinated alkenyl, formyl, C1-C3-alkylcarbonyl, and an aromatic radical Ar, R1 and R2 together with the carbon atoms to which they are attached, form a fused, saturated or unsaturated carbocyclic or heterocyclic ring, of 5, 6 or 7 members joined by C comprising 1 heteroatom, selected from nitrogen, oxygen and sulfur as ring member and 0, 1 or 2 additional heteroatoms, independently selected from O, S and N, as members of the ring, wherein the fused ring is not substituted or may carry 1, 2 or 3 substituents selected, independently of each other, from the group of radicals R4 defined below; R3 is hydrogen, OH, halogen, CN, nitro, C1-C6-alkyl, C1-C6-fluorinated alkyl, C1-C6-hydroxyalkyl, C1-C6-alkoxy-C1-C6-alkyl, C2-C6-alkenyl, C2 -C6-fluorinated alkenyl, C2-C6-alkynyl, C3-C7-cycloalkyl, C3-C7-fluorinated cycloalkyl, C1-C6-alkoxy, C1-C6-hydroxyalkoxy, C1-C6-alkoxy-C1-C6-alkoxy, C1 -C6-fluorinated alkoxy, C1-C6-alkylthio, C1-C6-fluorinated alkylthio, C1-C6-alkylsulfinyl, C1-C6-fluorinated alkylsulfinyl, C1-C6-alkylsulfonyl, C1-C6-alkylsulfonyl fluorinated, C1-C6-alkylcarbonyl , C1-C6-fluorinated alkylcarbonyl, C1-C6-alkylcarbonylamino, C1-C6-fluorinated alkylcarbonylamino, carboxy, C1-C6-fluorinated alkyloxycarbonyl, C1-C6-fluorinated alkyloxycarbonyl, NRaRb, C (O) -NReRf, NH-C (O ) -NReRr, NRaRb-C1-C6-alkylene, O-NRaRb, etc. and wherein R4 and R5 have the values defined in the specification and in the claims. |
| priorityDate | 2005-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1017.