| abstract |
This invention provides the compounds of formula (I). (see formula (I)) or a pharmaceutically acceptable ester or salt thereof, in which R1 and R2 independently represent hydrogen or the like; R3 represents aryl or the like; -X-Y- represents -CH2O- or the like, and n represents 0, 1 or 2, these compounds have ORL1 receptor antagonistic activity, and therefore, are useful for treating diseases or conditions such as pain, various CNS diseases, etc. |