abstract |
Process for the preparation of phosphatidylserine of formula (see formula) wherein R1 and R2 independently represent a saturated, monounsaturated or polyunsaturated acyl of C10-C30, X = OH or OM where M = alkali metal or alkaline earth metal, ammonium , alkylammonium (including the inner salt) including the transphosphatidylation reaction between the phosphatidylcholine of the general formula (see formula) wherein R1 and R2 and X have the meanings specified above, R3 = CH2-CH2-NH2 or CH2-CH2-N + (CH3) 3 and serine in form D, L or racemic form catalyzed by the enzyme phospholipase D (PLD), wherein said reaction is carried out in a hydroalcoholic medium containing an aliphatic alcohol and in the presence of a bivalent metal oxide . |