abstract |
The present invention relates to T3 mimetics containing phosphonic acid compounds and monosteres of the same stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of prodrugs, as well as their preparation and uses to prevent and / or treat metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome X and diabetes. |