| abstract |
The present invention relates to pharmaceutical compositions comprising certain carbamic acid compounds (for example, which inhibit the activity of HDAC (histone deacetylase)) (for example, PXD-101, N-hydroxy-3- (3-phenylsulfamoyl-phenyl) ) -acrylate measure)) and one or more additional ingredients selected from cyclodextrin, arginine, and meglumine. The present invention also relates to the use of such compositions, for example, in the inhibition of HDAC, and in the treatment of conditions mediated by HDAC, cancer, proliferative conditions, psoriasis, etc. |