| abstract |
The invention relates to a compound having the general formula I (see formula (I)) wherein: X represents CH2, C = O, C = S or CHOH, X represents CH2, C = O, C = S or CHOH , CH2, R1 represents an amino acid which is optionally substituted by one or more halogen atoms, preferably fluorine, or by one or more CF3 groups and n = 0.1 or 2, or X represents CH2, C = O, C = S or CHOH, R1 represents a peptide containing two amino acids, each amino acid is optionally substituted by one or two halogen atoms, preferably fluorine, or by one or more CF3 groups and n = 0 or 1, or XR1 represents PO3H or SO3H and n = 0.1 or 2; R2 represents H, XR1, a C1-C6 alkyl group, a C1-C6 aralkyl group or an aryl group, whereby the alkyl, aralkyl and aryl groups can be substituted by an NH2 amine, a COOH carboxylic group, one or more halogen atoms, preferably fluorine, or one or more CF3 groups; or the pharmaceutically acceptable addition, isomer, enantiomer and diastereoisomer salts of said compound, mixtures thereof, and pharmaceutical or cosmetic compositions comprising the same and the use thereof as an AGE inhibitor drug that traps reactive carbonyl compounds. |