| abstract |
This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as a vanyloid receptor antagonist (Vanyloid Receptor 1; VR1; TRPV1); and a pharmaceutical composition that contains them. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve damage, skin disorder, urinary bladder hypersensitivity; irritable bowel syndrome; fecal urgency, a respiratory disorder, skin irritation, eye or mucous membrane, duodenal stomach ulcer, inflammatory diseases, ear disease, and heart disease. |