| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f8c0982b0f02b1ed6d20a315370a3a3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-164 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0008
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-43
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y601-01002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5088
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-19 |
| filingDate |
2006-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5331affa1039960f8f4e3b0848b6b975
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c704686ae7d3e3aa7df0bb3d52df3033
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6b429f2cb1355f7f25c20567a04ed31 |
| publicationDate |
2007-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2007010384-A |
| titleOfInvention |
REVASCULARIZATION OF ISCHEMICAL RETINATED FABRIC AND SELECTION METHOD FOR THE SAME. |
| abstract |
The present invention provides a method of treatment to promote the beneficial physiological revascularization of ischemic retinal tissue. The method comprises administering to a mammal that suffers from a retinal vascular ischemia a therapeutically effective amount of an angiostatic fragment of triptofanil-tRNA synthetase (TrpRS), which consequently simultaneously inhibits pathological neovascularization while promoting beneficial physiological revascularization of damaged areas of the retina. In a preferred embodiment, the angiostatic TrpRS fragment is T2-TrpRS or T2-TrpRS-GD. Preferably, the mammal is a human patient suffering from retinal ischemia. A method of selection to identify and evaluate therapeutic agents to treat retinal neovascular diseases is also described. |
| priorityDate |
2005-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |