abstract |
The invention relates to novel macrocyclic compounds of the formula, wherein R1, R3, V1, V2, X1, X2, Y, Z, AR, AA and n are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16, 17, or 18, in the form of a free base or in the form of an acid addition salt, to its preparation, to its use as medicines and to medicines that comprise them. |