abstract |
The present invention relates to certain novelty compounds of formula (1), to the processes for preparing such compounds, to their usefulness in the modulation of nuclear hormone receptors - Liver X Receptor (LXR) to (NR1H3) and / or ???? (NR1H2) and in treating and / or preventing clinical conditions that include cardiovascular diseases such as atherosclerosis; inflammatory diseases, Alzheimer's disease, lipid disorders (dyslipidemias) whether or not associated with insulin resistance, type 2 diabetes and other manifestations of metabolic syndrome, methods for therapeutic use and pharmaceutical compositions containing them. |