abstract |
The present application refers to new tetrahydroquinoline derivatives of formula (I), in which R1 represents cyclohexyl or cyclopentyl, R2 and R3 respectively represent methyl or together form a cyclobutane, R4 represents cyclopropyl or isopropyl, as well as their salts, solvates and solvates of the salts, to a procedure for their preparation, for their use alone or in combinations for the treatment and / or prevention of diseases, as well as for their use for the preparation of medicaments, particularly as inhibitors of the transfer protein of cholesterol ester (CETP) for the treatment and / or prevention of cardiovascular diseases, particularly hypolipoproteinemias, dyslipidemias, hypertriglyceridemias, hyperlipidemias, hypercholesterolemias and arteriosclerosis. |