abstract |
The present invention relates to a method for the preparation of 1,2,2,2-tetrafluoroethyldifluoromethyl ether (CF3CHFOCHF2, Deflurane) which comprises reacting CF3CHCIOCHF2 (isoflurane) with hydrogen fluoride, in the presence of antimony pentafluoride, such so that deflurane is formed. |