http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2007005159-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1f874eb11d4775decc4fd06a6071a4c9 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D473-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D473-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2005-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bcc886f0beae9d3f655922982c57b40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b54bc96e0e3df190b689e636837963a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b12fde1e86e463ed9e56bad5b9cd690c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0895f6a73b865e27a992183ecfa5c63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afddfc2348d1e8584384dbf36f1c0d36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d148f7780adf250745a67daf7f93cdb0 |
| publicationDate | 2007-06-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2007005159-A |
| titleOfInvention | HIV INHIBITING BICYCLE PYRIMIDINE DERIVATIVES. |
| abstract | HIV replication inhibitors of formula (see formula) N-oxides, pharmaceutically acceptable addition salts, quaternary amines or their stereoisomeric forms, in which -a1 = a2-a3 = a4-is -CH = CH-CH = CH- , -N = CH-CH = CH-, -N = CH-N = CH-, -N = CH-CH = N, -N = N-CH = CH-; -b1 = b2-b3 = b4- is -CH = CH-CH = CH-, -N = CH-CH = CH-, -N = CH-N = CH-, -N = CH-CH = N, - N = N-CH = CH-; n and m is 0, 1, 2, 3 and in certain cases also 4, R1 is hydrogen; aryl, formyl, C 1-6 alkylcarbonyl; C1-6 alkyl optionally substituted; C1-6 alkyloxycarbonyl; R2 is OH; halogen; optionally substituted C1-6 alkyl, C2-6 alkenyl or C2-6 alkynyl; substituted carbonyl; carboxyl; CN; nitro; Not me; substituted amino; polyhalogenomethyl; polyhalogenomethylthio; -S (= O) PR6, C (= NH) R6; R2a is CN; amino, substituted amino, optionally substituted C1-6 alkyl; halogen; optionally substituted C1-6 alkoxy; substituted carbonyl; -CH = N-NH-C (= O) -R16; C1-6 alkyloxy optionally substituted; substituted C2-6 alkenyl or C2-6 alkynyl; -C (= N-O-R8) -C 1-4 alkyl; R7 or -X-R7; R3 is CN; Not me; C1-6 alkyl; halogen; C1-6 alkyloxy optionally substituted; substituted carbonyl; -CH = N-NH-C (= O) -R16; C1-6 substituted alkyl; C1-6 alkyloxy C1-6 alkyl optionally substituted; substituted C2-6 alkenyl or C2-6 alkynyl; -C (= N-O-R8) -C 1-4 alkyl; R7; R4 is halogen; OH; optionally substituted C1-6 alkyl, C2-6 alkenyl or C2-6 alkynyl; C3-7 cycloalkyl; C1-6 alkyloxy; WITH; nitro; C1-6 polyhalogenoalkyl; C1-6 polyhalogenoalkyloxy; substituted carbonyl; formyl; Not me; mono- or di (C1-4- alkyl) amino or R7; -A-B- is -CR5 = N-, -N = N-, -CH2-CH2-, -CS-NH-, -CO-NH-, -CH = CH-; pharmaceutical compositions comprising them; methods for the preparation of these compounds and these compositions; the use of these compounds for the prevention or treatment of HIV infection. |
| priorityDate | 2004-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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