| abstract |
The present invention provides steroid compounds (substituted which have a selective estrogen receptor activity according to formula (1), wherein R1 is H, C1-5 alkyl, C1-12 acyl, di (C1-5 alkyl ) aminocarbonyl, (C1-5 alkyl) oxycarbonyl or sulfamoyl, R2 is H, C1-3 alkyl, C2-3 alkenyl or C2-3 alkynyl and each of which may be optionally substituted by a halogen, R3 is C1-2 alkyl, ethenyl or ethynyl, and each of which may be optionally substituted by a halogen and R4 is H or C1-12 acyl. |