http://rdf.ncbi.nlm.nih.gov/pubchem/patent/MX-2007002716-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0e61263b84630539d1fc5281e3bd9ac4 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-02 |
| filingDate | 2005-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4484b45df40ce3f385aae1ff0b1dfe5b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d948c251fd0f18b2ce6ec673ec9bbf6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c1cb3e68a83da43c824317423e3c2d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f93c6ec045231f71fc21f7fdf52b31e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc7022e09567b1a87b92e65536a35245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a0975ac744ef94a795bcd0c7623e953 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1477713f5c94fe051c257830f6e8939 |
| publicationDate | 2008-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | MX-2007002716-A |
| titleOfInvention | FIBRATE COMPOUNDS THAT HAVE AGONISTIC ACTIVITY OF ACTIVATED RECEPTORS OF PEROXISOME PROFILER. |
| abstract | Derivatives that have PPAR agonist activity are provided. Derivatives include compounds and / or their pharmaceutically acceptable salts; the compounds having the formula (I) wherein A has the structure (II) or (III); X is chosen from -CH2, -O-, -NH-, and -S; And it is chosen from -O-, -NH, and -S-; Z that can be located in any substitution position is hydrogen or halogen; R1 and R2, which may be the same or different, are independently selected from hydrogen and C1-C8alkyl, or R1 and R2 together form a carbocyclic ring having 4 to 6 carbon atoms; R3 is chosen from C1-C8alkyl hydrogen, or R4 and R5 and R6 which may be the same or different, are independently selected from hydrogen and C1-C8alkyl, and n is 1 to 6. Various modalities and variants are provided. In accordance with other aspects, the invention also provides methods for producing an agonist activity of PPAR in a mammal, methods that include administering to the mammal an effective amount of certain derivatives of the first aspect of the invention, a method of producing an activity PPAR agonist and a PPAR agonist activity in a mammal, the method that includes administering to the mammal an effective activity of certain derivatives; and a pharmaceutical composition that includes derivatives of the first aspect of the invention and one or more pharmaceutically acceptable excipients. Several modalities and variants are provided. |
| priorityDate | 2004-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID425193155 http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID456171974 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID783 |
Total number of triples: 20.