| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24e76490bed88751680a5fef9bc73892 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K2217-075 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-4705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-51 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00 |
| filingDate |
2005-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d3650ccdfc96d6fc7cf58535423a7ce
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f1aa7bb29ea9ecec4539a3898c76862
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6ab86c2ee1adba259fa707f107dcd05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f8b433252f4e171eec64321c4e6914d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c17f0cef03f90c0da327f777a4f8307
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b0f055320f1c975f961f0e0bf72c1032
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31efd72aece5760f79553666df8c089e |
| publicationDate |
2007-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
MX-2007002379-A |
| titleOfInvention |
SYSTEMS AND METHODS FOR THE PRODUCTION OF PROTEINS. |
| abstract |
The invention relates to systems and methods for producing proteins of interest. The invention employs genetically engineered animal or plant cells that have modified protein folding or processing capabilities. In one aspect, the invention incorporates genetically modified cells comprising one or more recombinant expression cassettes which code for (1) a protein of interest and (2) a polypeptide that is functional in the non-folded protein response pathway (UPR) ) of the cells. Co-expression of the polypeptide significantly increases the yield of the protein of interest in genetically engineered cells. In one example, cells genetically manipulated with animal cells, and the co-expressed polypeptide is a component or modulator of a UPR pathway mediated by XBP1 or ATF6. |
| priorityDate |
2004-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |